刘庄教授学术报告“nanotechnology for innovative cancer therapies”
苏州大学
时间：2016年12月13日（周二）下午4:00
地点：化学楼三楼会议室
zhuang liu *
institute of functional nano & soft materials laboratory (funsom), soochow university suzhou, jiangsu , 215123 , china
starting from 2009, our group has been working on the development of functional nanomaterials for applications in biomedical imaging and cancer therapies. in the first part of this talk, i will introduce our latest efforts on the development of nanotechnology to enhance cancer radiation therapy (rt), one of three mainstream cancer treatment methods used in the clinic. we have uncovered that certain types of inorganic nanomaterials could absorb x-ray, acting as radio-sensitizers to enhance the efficacy of rt. with the help of nanotechnology, we could also modulate the tumor microenvironment (e.g. tumor hypoxia) to optimize rt cancer treatment. in the second part, i will then discuss our recent studies in the area of nano-immunotherapy. we have tried to combine photothermal therapy with immunotherapy using multifunctional nano-agents. stimulated by the tumor-associated antigens released after photothermal tumor ablation, the triggered immunological responses in combination with anti-ctla4 therapy to suppress the activity of regulatory t cells could result in effective inhibition of tumor cells remaining in the body, promising for treatment of cancer metastasis.
刘庄，苏州大学教授，博导，国家杰青。2004年北京大学获学士学位；2008年美国斯坦福大学获博士学位；2009年6月加入苏州大学功能纳米与软物质研究院。近年来在纳米生物医学材料与肿瘤纳米技术领域从事研究，共发表学术论文190余篇，论文总引用超过24,000次，sci h-index = 72。2012年获基金委优秀青年基金资助；2013年入选百千万人才工程国家级人选；2013年获江苏省杰出青年基金资助；2015年获国家杰出青年基金资助；2015年入选中组部万人计划“青年拔尖人才”；2016年入选科技部“中青年科技创新领军人才”。2015年受邀成为英国皇家化学会会士(fellow of the royal society of chemistry)。2015、2016年入选汤森路透社(thomson reuters)发布的“全球高引用科学家名录”（highly cited researchers）（化学、材料）。担任生物材料领域国际著名期刊biomaterials杂志副主编和多个国际主流期刊编委。